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Date: <2024-09-19 Thu>

Human Virome

Table of Contents

A symbiotic virus ecosystem

1. We are an ecosystem

00:00:27

We are an ecosystem of

  • 40 Trillion Cells
  • 40 Trillion Bacteria (The Microbiome)
    • The bacteria live in symbiosis
    • But some of them also attack us
  • 10 Trillion Viruses

2. Some viruses maintain balance

00:01:44

Most of the virus in Gut are bacteriophases and don't infect us

2.1. Lambdaphage

00:02:24

  • Kills Escherichia Coli (E. Coli) which is usually good (produces vitamin)
  • Lambdaphage keep the population of Escherichia Coli in check

3. Some actively help us

00:03:56

Virome needs us to thrive. So some viruses actively help us by injecting genes:

  • support gut mucus
  • break down complex carbohydrates
  • send signal to immune system, prevent autoimmune 00:04:23

3.1. Oncolytic Virus

00:07:23

Oncolytic Viruses hunt Cancer cells

  • Newcastle Disease Virus
  • Reovirus
  • 00:08:40 Seem to go well with Chemotherapy and Radiation too

4. Some actively affect us

00:04:39

Some viruses actively harm us, by modifying bacteria

  • 00:04:59 CTXφ Modify Vibrio Cholerea
  • φ Sa3ms hunts Staphylococcus aureus and makes it dangerous for us causing T cell to go crazy (00:06:25)

References

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